DESCOVY had less impact on bone health than TRUVADA

Bone mineral density, or BMD, is a good gauge of bone health. And for most people, our bones actually continue to grow into our 30s.

For people taking DESCOVY in the DISCOVER trial, their BMD was less impacted than those taking TRUVADA (at about 2 years or ~96 weeks):
The lower back*: Descovy (144 people) +1.0%, Truvada (140 people) -1.4%; The hip bone: Descovy (140 people) +0.6%, Truvada (137 people) -1.0%

BMD was measured in study participants when they entered the study and again at 2 years from the start of the study.
The long-term significance of these changes in BMD is not known.

*Also known as the lumbar spine. Your lumbar spine consists of the five bones (vertebra) in your lower back.